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Acide Alendronique [Inn-French] en es it fr

Acide Alendronique [Inn-French] Brand names, Acide Alendronique [Inn-French] Analogs

Acide Alendronique [Inn-French] Brand Names Mixture

  • No information avaliable

Acide Alendronique [Inn-French] Chemical_Formula

C4H13NO7P2

Acide Alendronique [Inn-French] RX_link

http://www.rxlist.com/cgi/generic/alendron.htm

Acide Alendronique [Inn-French] fda sheet

Acide_Alendronique_[Inn-French] FDA

Acide Alendronique [Inn-French] msds (material safety sheet)

Acide_Alendronique_[Inn-French] MSDS

Acide Alendronique [Inn-French] Synthesis Reference

M. I. Kabachnik et al., Bull. Acad. Sci. USSR,.27, 374 (1978)

Acide Alendronique [Inn-French] Molecular Weight

249.096 g/mol

Acide Alendronique [Inn-French] Melting Point

233 - 235 oC

Acide Alendronique [Inn-French] H2O Solubility

1mg/L

Acide Alendronique [Inn-French] State

Solid

Acide Alendronique [Inn-French] LogP

-3.198

Acide Alendronique [Inn-French] Dosage Forms

Tablets (6.53, 13.05, 45.68, 52.21 or 91.37 mg of alendronate monosodium salt trihydrate)

Acide Alendronique [Inn-French] Indication

For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.

Acide Alendronique [Inn-French] Pharmacology

Alendronate, a second-generation bisphosphonate is the first member of a group of drugs which strengthens bone. Alendronate is used to reduce hypercalcemia in tumor-induced bone disease, to treat corticosteroid-induced osteoporosis and Paget's disease, and to prevent osteoporosis in postmenopausal women.

Acide Alendronique [Inn-French] Absorption

Relative to an intravenous (IV) reference dose, the mean oral bioavailability of alendronate in women was 0.7% for doses ranging from 5 to 40 mg when administered after an overnight fast and two hours before a standardized breakfast. Oral bioavailability of the 10 mg tablet in men (0.59%) was similar to that in women (0.78%) when administered after an overnight fast and 2 hours before breakfast.

Acide Alendronique [Inn-French] side effects and Toxicity

Alendronate can damage the esophagus both by toxicity from the medication itself and by nonspecific irritation secondary to contact between the pill and the esophageal mucosa, similar to other cases of "pill esophagitis."

Acide Alendronique [Inn-French] Patient Information

Acide Alendronique [Inn-French] Organisms Affected

Humans and other mammals